Graduate Pharmacy Aptitude Test Syllabus

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GPAT Syllabus

GPAT Exam Syllabus covers different subjects such as Pharmaceutics, Pharmaceutical Chemistry, Pharmacology, Pharmacognosy, and other related disciplines. To score well in GPAT, candidates should go through the entire syllabus and focus on the topics that require more attention. They should refer to relevant textbooks, study materials, and previous year’s question papers to prepare effectively for the exam.

Exam Analysis 2025
Subjects Topics
Physical Chemistry
  • Composition and physical states of matter
  • Colligative Properties
  • Thermodynamics
  • Refractive Index
  • Solutions
  • Electrochemistry
  • Ionic Equilibrium
  • Kinetics
Physical Pharmacy
  • Matter, properties of matter
  • Micromeritics and powder rheology
  • Surface and Interfacial Phenomena
  • Viscosity and Rheology
  • Dispersion Systems
  • Complexation
  • Buffer
  • Solubility
Organic Chemistry
  • General Principles
  • Different classes of compounds
  • Protection and deprotection of groups
  • Aromaticity and chemistry of aromatic compounds
  • Different aromatic classes of compounds
  • Polycyclic aromatic hydrocarbons
  • Carbonyl Chemistry
  • Heterocyclic Chemistry
  • Bridged rings
  • Kinetic & thermodynamic control
  • Stereochemistry
  • Carbohydrates
  • Amino acids & proteins
  • Pericyclic reactions
Pharmaceutical Chemistry
  • Pharmaceutical Inorganic Chemistry
    • Pharmaceutical Impurities
    • Monographs
    • Isotopes
    • Dentifrices, desensitizing agents, & anticaries agents
  • Medicinal Chemistry
    • Therapeutic classes of drugs
    • Various classes of therapeutic agents
    • Different classes of therapeutic drugs
Pharmaceutics
  • Pharmacy Profession & Introduction to Pharmaceuticals
  • Introduction to dosage form
  • Sources of drug information
  • Allopathic dosage form
  • Crude extract
  • Allergenic extract
  • Biological products
  • Pharmaceutical Plant, location, layout
  • Dosage Form Necessities and Additives
  • Powders
  • Capsules
  • Tablets
  • Parenterals - a product requiring sterile packaging
  • Suspensions
  • Emulsions
  • Suppositories
  • Semisolids
  • Liquids(solutions, syrups, elixirs, spirits, aromatic water, liquid for external uses)
  • Pharmaceutical Aerosols
  • Ophthalmic preparations
  • Preformulations
  • Stability of formulated products
  • Prolonged Action Pharmaceuticals
  • Novel Drug Delivery System
  • GMP and Validation
  • Packaging Materials
  • Cosmetics
  • Pilot plant scale-up techniques
Pharmacology
  • General Pharmacology
  • Neurohumoral transmission in the autonomic and central nervous system
  • Pharmacology of the peripheral nervous system
  • Pharmacology of the Central Nervous System
  • Pharmacology of the cardiovascular system
  • Drugs acting on the urinary system
  • Drugs acting on the Respiratory system
  • Pharmacology of the Endocrine System
  • Dosage Form Necessities and Additives
  • Chemotherapy
  • Autacoids and Their Antagonists
  • Pharmacology of drugs acting on the gastrointestinal tract
  • Chronopharmacology
  • Immunopharmacology
  • Vitamins & Minerals
  • Principles of toxicology
Pharmacognosy
  • Introductory Pharmacognosy
  • Classification of crude drugs
  • Factors influencing the quality of crude drugs
  • Techniques in microscopy
  • Introduction to phytoconstituents
  • Principles of plant classification
  • Pharmaceutical aids
  • Animal products
  • Plant products
  • Toxic drugs
  • Enzymes
  • Natural pesticides and insecticides
  • Adulteration and evaluation of crude drugs
  • Quantitative microscopy
  • Biogenetic pathways
  • Carbohydrates & lipids
  • Tannins
  • Volatile oils
  • Resinous drugs
  • Glycosides
  • Alkaloids
  • Extraction and Isolation Techniques
  • Phytopharmaceuticals
  • Quality control and Standardization of herbal drugs
  • Herbal formulations
  • Worldwide trade of crude drugs and volatile oils
  • Herbal cosmetics
  • Traditional herbal drugs
  • Plant-based industries and research institutes in India
  • Patents
  • Ayurvedic system of medicine
  • Homoeopathic system of medicine
Pharmaceutical Analysis
  • Importance of quality control in pharmacy
  • Acid-base titrations
  • Non-aqueous titrations
  • Oxidation-reduction titrations
  • Precipitation titrations
  • Complexometric titrations
  • Gravimetry
  • Extraction techniques
  • Potentiometry
  • Miscellaneous methods of analysis
  • Calibration
  • General principles of spectroscopy
  • Ultraviolet-visible Spectrometry
  • Spectrofluorimetry
  • Flame photometry & atomic absorption spectrometry 16. Infrared spectrometry
  • Proton nuclear magnetic resonance spectrometry
  • Mass spectrometry
  • Polarography
  • Nephelometry & Turbidimetry
  • Chromatography
  • Miscellaneous
Biochemistry
  • Cell
  • Carbohydrates
  • Proteins
  • Lipids
  • Vitamins
  • Biological oxidations & reductions
  • Enzymes
  • Nucleic acids
  • Hereditary diseases
Biotechnology
  • Plant Cell and Tissue Culture
  • Animal Cell Culture
  • Fermentation Technology and Industrial Microbiology.
  • Recombinant DNA Technology
  • Process and Applications
  • Biotechnology-Derived Products
Microbiology
  • Introduction to Microbiology
  • Microscopy and staining technique
  • Biology of Microorganisms
  • Fungi and Viruses
  • Aseptic Technique
  • Sterilization & Disinfection
  • Microbial spoilage
  • Vaccines & Sera
  • Microbial Assay
Pathophysiology
  • Basic principles of cell injury and adaptation
  • Basic mechanisms of inflammation and repair
  • Disorders of fluid, electrolyte, and acid-base balance
  • Disorders of homeostasis: white blood cells, lymphoid tissues, and red blood cells related diseases
  • Immunopathology including amyloidosis
  • Infectious diseases
  • Neoplastic diseases
  • Pathophysiology of common diseases
  • Laboratory tests for Liver function tests and kidney function tests
Biopharmaceutics and Pharmacokinetics
  • Bio-pharmaceutics
  • Bio-availability & Bio-equivalence
  • Bio-pharmaceutical statistics
Clinical Pharmacy and Therapeutics Basic concepts and general principles
Human Anatomy and Physiology
  • Cell physiology
  • The Blood
  • Gastrointestinal tract
  • Respiratory System
  • Autonomic nervous system
  • Sense organs
  • Skeletal System
  • Central Nervous System
  • Urinary System
  • Endocrine Glands
  • Reproductive System
  • Cardiovascular system
  • Lymphatic system
Pharmaceutical Engineering
  • Fluid flow
  • Heat transfer
  • Evaporation
  • Distillation
  • Drying
  • Size reduction and size separation
  • Extraction
  • Mixing
  • Crystallisation
  • Filtration and Centrifugation
  • Dehumidification and humidity control
  • Refrigeration and air conditioning
  • Material of construction
  • Automated process control systems
  • Industrial hazards & safety precautions
Pharmaceutical Management
  • Introduction to management
  • Planning and Forecasting
  • Organization
  • Research Management
  • Inventory Management
  • Communication
  • Marketing Research
  • Leadership and motivation
  • Human resource and development (HRD)
  • GATT
  • World trade organization (WTO) and trade-related intellectual property rights (TRIPS)
  • Standard institutions and regulatory authorities
Pharmaceutical Jurisprudence Basic Concepts like historical background, relevant acts, and rules
Dispensing and Hospital Pharmacy
  • Basic Concepts
  • Compounding and dispensing of certain prescriptions
  • Reading and counselling of prescriptions from the clinical practice

Pharmaceutics, Pharmaceutical Chemistry, Pharmacology, Pharmacognosy, and other relevant topics are included in the GPAT syllabus.
Pharmacodynamics, immunopharmacology, adverse drug reactions, chemotherapy are a few crucial areas of pharmacology for the GPAT.
For the GPAT, organic chemistry, medicinal chemistry, stereochemistry, and spectroscopy are a few key topics in pharmaceutical chemistry.

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